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doi: 10.1007/s1110201607782 157 SomozaGMPeterRE

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In: Goodman and Gilmans the pharmacological basis of therapeutics

In particular, SKN increased nitric oxide production through upregulation of endothelial nitric oxide synthase and proliferator-activated receptor alpha expression, while simultaneously decreasing iNOS, COX-2, and other oxidative markers